Insights into the dynamics of Hybrid Methods through a range of biological examples. A hands on approach

Duration: 47 mins 27 secs
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Description: Sunkara, V (Freie Universität Berlin, Konrad-Zuse-Zentrum für Informationstechnik Berlin)
Thursday 7th April 2016 - 11:45 to 12:30
 
Created: 2016-04-12 10:56
Collection: Stochastic Dynamical Systems in Biology: Numerical Methods and Applications
Publisher: Isaac Newton Institute
Copyright: Sunkara, V
Language: eng (English)
Distribution: World     (downloadable)
Explicit content: No
Aspect Ratio: 16:9
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Trailer: UCS Default
 
Abstract: Biological systems can emerge complexity from simple yet multitude of interactions. Capturing such biological phenomenon mathematically for predictions and inference is being actively researched. Computing systems where the interacting components are inherently stochastic demands large amounts of computational power. Recently, splitting the dynamics of the system into deterministic and stochastic components has been a new strategy for computing biological networks. This hybrid strategy drastically reduces the number of equations to solve, however, the new equations are naturally stiff and nonlinear. Hybrid models are a strong candidate as a numerical method for probing large biological networks with intrinsic stochasticity. In this talk we will take on a new mathematical and numerical perspective of hybrid models. Through many biological examples, we will aim to gain insight into the benefits and stumbling blocks of the hybrid framework.

Related Links

https://github.com/vikramsunkara/PyME - PyME: Python base CME solver.
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