The Role of Uncertainty in Mathematical Modelling of Pandemics

The Role of Uncertainty in Mathematical Modelling of Pandemics's image
Created: 2022-02-11 13:27
Institution: Isaac Newton Institute for Mathematical Sciences
Editors' group: Editors group for "Isaac Newton Institute for Mathematical Sciences".
Description: Background
There is an urgent need to advance the reliability and reproducibility of all forms of computer-based calculations. In an experimental setting, it is often common practice to provide not only measured values themselves, but also an estimate of the uncertainty in the measurements. Yet this is not yet standard practice when presenting predictions made by computational models.

Computational methods are becoming increasingly important for decision-making and thus a similar approach is needed to make computational predictions actionable, since virtually all models are contaminated by several sources of uncertainty. Sources of uncertainty originate in the imperfectly known input parameters assumptions made within the mathematical form of the model, and the influence of stochastic effects. Uncertainty quantification is a challenging field that combines scientific models, statistics, high-performance computing, and increasingly machine learning methods.

The mathematical sciences have a key role to play in addressing these challenges. In this event series, the Newton Gateway is working with members of the EPSRC-funded SEAVEA project. The work of the project seeks to address such challenges through the promotion and development of an open-source software toolkit for verification, validation and uncertainty quantification (VVUQ). This is optimised for efficient execution on many platforms including those at the current petascale and the emerging exascale. These capabilities offer new opportunities for simulations in fields as diverse as fusion, weather and climate modelling, epidemiology, advanced materials, biomedicine and many other domains.

Aims and Objectives
A series of three half-day science events is planned between 8th -10th February 2022 which will highlight key aspects of the research, bringing together relevant stakeholders across academia, industry and government. It will be delivered as a RAMP Continuity Network activity.

The event series has a focus on uncertainty modelling for epidemiology and pandemics, but will also highlight new opportunities for simulations in fields as diverse as fusion, weather and climate modelling, advanced materials, biomedicine and many other domains. Sessions will be spread across the three half days as follows:

VVUQ Fundamentals with a Focus on Epidemiology and Pandemics
Wider Applications of VVUQ Methods
Challenges and Advanced Methods for Epidemiological Modelling
Website: https://gateway.newton.ac.uk/event/tgm110
 

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Bayesian real-time epidemic monitoring of Covid-19


   27 views

Angelos Alexopoulos; MRC Biostatistics Unit
10 February 2022 – 15:10 to 15:35

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


Calibration Issues in Epidemiological Modelling


   6 views

TJ McKinley; University of Exeter
10 February 2022 – 14:00 to 14:25

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


Fundamental Principles of Reproducibility


   5 views

Odd Erik Gundersen; Norwegian University of Science and Technology
8 February 2022 – 14:00 to 14:25

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


Model uncertainty in turbulent fluid dynamics


   5 views

Daan Crommelin; Centrum voor Wiskunde en Informatica (CWI); Universiteit van Amsterdam
9 February 2022 – 15:10 to 15:35

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


Molecular Dynamics


   2 views

Peter Coveney; University College London
9 February 2022 – 15:35 to 16:00

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


Problems with Combining Models in Absence of Uncertainty Quantification


   6 views

Veronica Bowman; Defence Science and Technology Laboratory
10 February 2022 – 13:35 to 14:00

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Tue 15 Feb 2022


Quantifying Uncertainty in Assessment of Possible Exoplanet Biosignatures


   13 views

Peter Vickers; Durham University
9 February 2022 – 16:20 to 16:40

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


State of the Art Methods and Tools in VVUQ


   5 views

Diana Suleimenova; Brunel University
8 February 2022 – 15:35 to 16:00

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


The Impact of Uncertainty on the CovidSim Pandemic Code


   22 views

Wouter Edeling; Centrum voor Wiskunde en Informatica (CWI)
8 February 2022 – 14:25 to 14:50

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


UQ in Modelling of Fusion Power Plants for the UK National Grid


   6 views

Rob Akers, Wayne Arter; United Kingdom Atomic Energy Authority
9 February 2022 – 13:35 to 14:00

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022


Very Large Parameter Problems


   7 views

Wouter Edeling; Centrum voor Wiskunde en Informatica (CWI)
10 February 2022 – 14:25 to 14:50

Collection: The Role of Uncertainty in Mathematical Modelling of Pandemics

Institution: Isaac Newton Institute for Mathematical Sciences

Created: Fri 11 Feb 2022