Analysis of whole cancer genomes

29 mins,  121.50 MB,  Flash Video  484x272,  50.0 fps,  44100 Hz,  572.04 kbits/sec
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Description: Campbell, P (Wellcome Trust Sanger Institute)
Wednesday 14 July 2010, 16:00-16:30
 
Created: 2010-07-15 15:39
Collection: Statistical Challenges Arising from Genome Resequencing
Publisher: Isaac Newton Institute
Copyright: Campbell, P
Language: eng (English)
Distribution: World     (downloadable)
Credits:
Author:  Campbell, P
Producer:  Steve Greenham
Explicit content: No
Aspect Ratio: 16:9
Screencast: No
Bumper: UCS Default
Trailer: UCS Default
 
Abstract: Massively parallel sequencing technologies have revolutionized the field of cancer genomics. On a single platform, it is now possible to identify all somatically acquired mutations of all classes in a given cancer sample in real time. However, a number of challenges to interpreting the data exist, and necessitate the development of carefully tested bioinformatic algorithms. I will present an overview of our approaches for handling the data, focusing on the practical issues, common artefacts and challenges of current methodologies.
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