Lecture 15 (University of Cambrdige). Polymer model, mean looping time and interpretation of Hi-C data (Enounter frequencies data)
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Description: |
Holcman, D (CNRS - Ecole Normale Superieure Paris)
Friday 17th June 2016 - 14:15 to 17:00 |
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Created: | 2016-07-18 15:00 |
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Collection: | Stochastic Dynamical Systems in Biology: Numerical Methods and Applications |
Publisher: | Isaac Newton Institute |
Copyright: | Holcman, D |
Language: | eng (English) |
Distribution: | World (downloadable) |
Explicit content: | No |
Aspect Ratio: | 16:9 |
Screencast: | No |
Bumper: | UCS Default |
Trailer: | UCS Default |
Abstract: | In this talk, I will present the computation of the mean time for a Rouse polymer to loop in free and confined domains. The results are used to extract information (such the radius of confinement) from Hi-C data for the chromatin organization. The methods is based on the asymptotic analysis of the Fokker-Planck equation. |
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