Lecture 15 (University of Cambrdige). Polymer model, mean looping time and interpretation of Hi-C data (Enounter frequencies data)

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Description: Holcman, D (CNRS - Ecole Normale Superieure Paris)
Friday 17th June 2016 - 14:15 to 17:00
 
Created: 2016-07-18 15:00
Collection: Stochastic Dynamical Systems in Biology: Numerical Methods and Applications
Publisher: Isaac Newton Institute
Copyright: Holcman, D
Language: eng (English)
Distribution: World     (downloadable)
Explicit content: No
Aspect Ratio: 16:9
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Bumper: UCS Default
Trailer: UCS Default
 
Abstract: In this talk, I will present the computation of the mean time for a Rouse polymer to loop in free and confined domains. The results are used to extract information (such the radius of confinement) from Hi-C data for the chromatin organization. The methods is based on the asymptotic analysis of the Fokker-Planck equation.
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