Interacting-Particle Reaction-Diffusion Simulations: Endocytosis
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About this item
| Description: |
Noe, F (Freie Universität Berlin)
Tuesday 21st June 2016 - 11:00 to 11:45 |
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| Created: | 2016-07-04 14:33 |
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| Collection: | Stochastic Dynamical Systems in Biology: Numerical Methods and Applications |
| Publisher: | Isaac Newton Institute |
| Copyright: | Noe, F |
| Language: | eng (English) |
| Distribution: |
World
(downloadable)
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| Explicit content: | No |
| Aspect Ratio: | 16:9 |
| Screencast: | No |
| Bumper: | UCS Default |
| Trailer: | UCS Default |
| Abstract: | We have introduced interacting-particle reaction-diffusion (iPRD) simulations as a hybrid between molecular dynamics simulations and particle-based reaction-diffusion simulations. iPRD is a suitable modeling framework for many cellular signaling processes, especially such processes involving dense protein mixtures, supramolecular architectures or protein scaffolds at membranes. I will introduce to the theory behind iPRD and present computational algorithms.
One of our key application areas is clathrin-mediated endocytosis in neurons, and I will briefly elude to simulations of protein recruitment to clathrin-coated pits and the interplay between membrane-associated proteins and membrane deformation in endocytosis. Related Links http://readdy-project.org |
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