Four arguments against the reaction-diffusion master equation (and one in its favour).

45 mins 47 secs,  232.49 MB,  WebM  640x360,  29.97 fps,  44100 Hz,  693.32 kbits/sec
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Description: Smith, S (University of Edinburgh)
Tuesday 31st May 2016 - 15:00 to 16:00
 
Created: 2016-06-28 12:51
Collection: Stochastic Dynamical Systems in Biology: Numerical Methods and Applications
Publisher: Isaac Newton Institute
Copyright: Smith, S
Language: eng (English)
Distribution: World     (downloadable)
Explicit content: No
Aspect Ratio: 16:9
Screencast: No
Bumper: UCS Default
Trailer: UCS Default
 
Abstract: The reaction-diffusion master equation (RDME) is a well-established and popular lattice-based mathematical description of spatial stochastic chemical systems. A well-known argument against the RDME is that it gives absurd results in the limit of small lattice spacing: this fact has led researchers to develop modified RDMEs which avoid this problem. In this talk, I will offer three further scenarios in which the RDME cannot be considered an accurate description of the underlying physical process. I subsequently argue that there is only a tiny class of problems for which the RDME is the most appropriate route to a solution. I will conclude by offering a beautiful problem from this tiny class to which the RDME provides a remarkable and counterintuitive solution.
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