Nonlocal models for interaction driven cell movement
59 mins 26 secs,
108.71 MB,
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About this item
| Description: |
Gerisch, A (Technische Universität Darmstadt)
Friday 11th December 2015 - 11:30 to 12:30 |
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| Created: | 2015-12-21 11:33 |
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| Collection: | Coupling Geometric PDEs with Physics for Cell Morphology, Motility and Pattern Formation |
| Publisher: | Isaac Newton Institute |
| Copyright: | Gerisch, A |
| Language: | eng (English) |
| Distribution: |
World
(downloadable)
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| Explicit content: | No |
| Aspect Ratio: | 16:9 |
| Screencast: | No |
| Bumper: | UCS Default |
| Trailer: | UCS Default |
| Abstract: | Authors: A. Gerisch, K.J. Painter, J.M. Bloomfield, J.A. Sherratt
Instructing others to move is fundamental for many populations, whether animal or cellular. Often such commands are transmitted by contact, such that an instruction is relayed directly from signaller to receiver: for cells, this can occur via receptor–ligand mediated interactions at their membranes, potentially at a distance if a cell extends long filopodia. Given that commands ranging from attractive to repelling can be transmitted over variable distances and between cells of the same (homotypic) or different (heterotypic) type, these mechanisms can clearly have a significant impact on the organisation of a tissue. In this talk we consider nonlocal models based on integro-PDEs to model contact based cell movement. We describe some specific applications and highlight the mathematical and numerical challenges that the models present. |
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