Contributed Talk 1: Computational models of spatial behaviour of microbial communities
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About this item
| Description: |
Kalvala, S (University of Warwick)
Wednesday 10 September 2014, 16:55-17:10 |
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| Created: | 2014-09-15 14:01 |
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| Collection: | Understanding Microbial Communities; Function, Structure and Dynamics |
| Publisher: | Isaac Newton Institute |
| Copyright: | Kalvala, S |
| Language: | eng (English) |
| Distribution: |
World
(downloadable)
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| Explicit content: | No |
| Aspect Ratio: | 16:9 |
| Screencast: | No |
| Bumper: | UCS Default |
| Trailer: | UCS Default |
| Abstract: | Computational simulations are now an important component of the toolkit for studying biological systems. While it is easy to simulate well-mixed solutions in order to model intra-cellular processes, it is more difficult to capture spatial phenomena characterizing microbial communities. The problem is compounded because we need to capture not only inter-cellular communication but also changing configurations, with microbes that move, change shape, and create new communication channels.
In this talk I will review some of the methodologies that have been developed for spatially-aware computational modelling of microbial communities and the limitations of these methodologies. I will also present some of our results in capturing some of the intriguing behaviour of myxobacteria communities (namely rippling and the formation of fruiting bodies) via a spatial simulation based on the Cellular Potts Model. |
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