Contributed Talk 1: Computational models of spatial behaviour of microbial communities
15 mins 52 secs,
29.03 MB,
MP3
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Description: |
Kalvala, S (University of Warwick)
Wednesday 10 September 2014, 16:55-17:10 |
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Created: | 2014-09-15 14:01 |
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Collection: | Understanding Microbial Communities; Function, Structure and Dynamics |
Publisher: | Isaac Newton Institute |
Copyright: | Kalvala, S |
Language: | eng (English) |
Distribution: | World (downloadable) |
Explicit content: | No |
Aspect Ratio: | 16:9 |
Screencast: | No |
Bumper: | UCS Default |
Trailer: | UCS Default |
Abstract: | Computational simulations are now an important component of the toolkit for studying biological systems. While it is easy to simulate well-mixed solutions in order to model intra-cellular processes, it is more difficult to capture spatial phenomena characterizing microbial communities. The problem is compounded because we need to capture not only inter-cellular communication but also changing configurations, with microbes that move, change shape, and create new communication channels.
In this talk I will review some of the methodologies that have been developed for spatially-aware computational modelling of microbial communities and the limitations of these methodologies. I will also present some of our results in capturing some of the intriguing behaviour of myxobacteria communities (namely rippling and the formation of fruiting bodies) via a spatial simulation based on the Cellular Potts Model. |
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