Cardiac Physiome Project
| Created: | 2009-07-22 15:47 |
|---|---|
| Institution: | Isaac Newton Institute for Mathematical Sciences |
| Editors' group: | SMS Editors group for the Newton Institute |
| Description: | Predicting physiological behaviour from experimental data combined with environmental influences is a compelling, but unfulfilled, goal of post-genomic biology. This undeniably ambitious goal is the aim of the Physiome Project and its subset the Cardiome Project which is an international effort to build a biophysically based multi-scale mathematical model of the heart. To achieve this goal requires further development of the current generation of advanced cardiac models which span an already diverse set of mathematical representations from stochastic sub-cellular regulation models to whole-organ-based sets of coupled partial differential equations. The focus of this programme will be on the development and application of the mathematical techniques which underpin the ongoing extension of this approach, and specifically to:
* integrate data from disparate sources into a common quantitative framework; * examine the complex cause and effect relationships which exist across many temporal and spatial orders of magnitude in physiology; * determine the appropriate level of detail to capture observable phenomena and the closely related issue of parameter identifiability; * examine issues of model inheritance and multi-scale coupling for combining existing models together to create extended frameworks; * define standards for the constituent electrical, mechanical and vascular classes of cardiac models. Read more at: www.newton.ac.uk/programmes/CPP/ |
Media items
This collection contains 56 media items.
Media items
3D/1D geometrical multiscale modeling of vascular networks
817 views
Passerini, T (Emory)
Tuesday 21 July 2009, 10:45-11:00
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
A novel approach to multidomain modeling of electrical conduction in cardiac tissue
801 views
Sachse, F (Utah)
Monday 20 July 2009, 16:15-16:30
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
A posteriori error estimation and adaptivity for operator decomposition methods
424 views
Tavener, S (Colorado State)
Tuesday 21 July 2009, 14:15-14:30
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Thu 23 Jul 2009
Adaptive Tetrahedral Meshing for Personalized Cardiac Simulations
677 views
Delingette, H (INRIA)
Thursday 23 July 2009, 14:45-15:00
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Mon 27 Jul 2009
An attempt for dialectics: what can we learn from interdigitating wet and dry research into structure and function...
370 views
Kohl, P (Oxford)
Tuesday 21 July 2009, 14:45-15:00
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Thu 23 Jul 2009
Building detailed cardiac electrophysiological models from high-resolution images
618 views
Grau, V (Oxford)
Wednesday 22 July 2009, 10:45-11:00
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Fri 24 Jul 2009
Building tissue mechanics into novel types of multi-scale models
751 views
Jensen, O (Nottingham)
Friday 24 July 2009, 10:15-10:30
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 29 Jul 2009
CellML language and tools supporting the cardiac physiome
499 views
Nielsen, P (Auckland)
Friday 24 July 2009, 10:45-11:00
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 29 Jul 2009
Clinically observed phenomena on cardiac energetics in heart failure emerge from simulations of cardiac metabolism
635 views
Beard, D (Medical College of Wisconsin)
Monday 20 July 2009, 12:15-12:30
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
Closing comments
601 views
Smith, N (Oxford)
Friday 24 July 2009, 11:45-12:00
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 29 Jul 2009
Commented Poster Session 1
421 views
Commented Posters at the The Cardiac Physiome: Multi-scale and Multi-physics Mathematical Modelling Applied to the Heart conference.
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
Commented Poster Session 2
416 views
Commented Posters at the The Cardiac Physiome: Multi-scale and Multi-physics Mathematical Modelling Applied to the Heart conference.
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Fri 24 Jul 2009
Computational modelling to investigate the role of aging and species on arterial branch lesion patterns
1,136 views
Sherwin, S (Imperial College London)
Wednesday 22 July 2009, 13:45-14:00
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Thu 21 Jan 2010
Connexins, buffers and mitochondria: novel pH/Ca2+ regulators in heart
722 views
Vaughan-Jones, R (Oxford)
Monday 20 July 2009, 10:00-10:45
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
Development and testing of Cardiac Physiome cell model parts in skeletal muscle
432 views
Jeneson, J (TU, Eindhoven)
Monday 20 July 2009, 12:00-12:15
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
Development of a virtual heart - Part l
902 views
Boyett, M (Manchester)
Monday 20 July 2009, 14:30-14:45
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
Development of a virtual heart - Part ll
714 views
Zhang, H (Manchester)
Monday 20 July 2009, 14:45-15:00
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
Dynamic modelling of chorded mitral valve
563 views
Luo, X (Glasgow)
Wednesday 22 July 2009, 14:30-14:45
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Fri 24 Jul 2009
Electrophysiological metric and geometry of the heart
897 views
Panfilov, S (Utrecht)
Monday 20 July 2009, 15:30-15:45
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Wed 22 Jul 2009
Fluid solid interaction for vascular applications
758 views
Hose, R (Sheffield)
Wednesday 22 July 2009, 13:30-13:45
Collection: Cardiac Physiome Project
Institution: Isaac Newton Institute for Mathematical Sciences
Created: Fri 24 Jul 2009